Esmolol vs Fentanyl for Intubation Response
Author Information
Author(s): Shobhana Gupta, Purvi Tank
Primary Institution: Medical College, Jamnagar, Gujarat, India
Hypothesis
Is esmolol more effective than fentanyl in reducing hemodynamic responses during laryngoscopy and intubation?
Conclusion
Esmolol is more effective than fentanyl in reducing heart rate increases during laryngoscopy and intubation.
Supporting Evidence
- Esmolol significantly reduced heart rate increases compared to the control group.
- The rise in blood pressure was less in the esmolol group than in the control group.
- No significant rise in heart rate was observed in the esmolol group at any time interval.
Takeaway
This study looked at two medicines, esmolol and fentanyl, to see which one helps keep your heart rate steady when doctors put a tube in your throat. Esmolol worked better!
Methodology
90 adult patients were divided into three groups: one received esmolol, another fentanyl, and the control group received saline before intubation.
Potential Biases
Potential bias in patient selection and exclusion criteria.
Limitations
The study excluded patients with difficult intubation and those with cardiovascular issues.
Participant Demographics
Patients aged 15-55, ASA grade I and II, weighing 35-60 kg.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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