Significant association between three atherosclerosis indexes and stroke risk: A national representative study
2024

Atherosclerosis Indexes and Stroke Risk in Older Adults

Sample size: 21913 publication 10 minutes Evidence: high

Author Information

Author(s): Wang Xin, Wu Lili, Shu Peng, Yu Wei, Yu Wangfang

Primary Institution: Department of Neurosurgery, Beilun District People’s Hospital, Ningbo, Zhejiang, China

Hypothesis

The study aims to evaluate the associations of three atherosclerosis indexes with stroke in a population aged 65 years and older.

Conclusion

The three atherosclerosis indexes studied—the AIP, CRI-I, and CRI-II—were found to be predictors of stroke in a Chinese population.

Supporting Evidence

  • High AIPs were associated with a high risk of stroke.
  • High CRI-I and CRI-II values were significantly correlated with an increased risk of stroke.
  • Subgroup analyses suggested that the predictive power of atherosclerosis indexes varied by sex and lifestyle factors.

Takeaway

This study found that certain blood tests can help predict the risk of having a stroke in older people.

Methodology

The study used data from the China Health and Retirement Longitudinal Study and applied multivariate logistic regression models to analyze the associations.

Limitations

The study's findings may not be generalizable to younger populations or those outside of China.

Participant Demographics

Participants were aged 65 years and older, with a sample size of 21,913 from various provinces in China.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI: 1.07–2.08

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0315396

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