Oestrogen and Progesterone Receptors in Breast Cancer
Author Information
Author(s): A. Alanko, E. Heinonen, T.M. Scheinin, E.-M. Tolppanen, R. Vihko
Primary Institution: Helsinki University Central Hospital
Hypothesis
Is there a relationship between oestrogen and progesterone receptor status and disease-free interval in primary breast cancer?
Conclusion
The study found no significant relationship between oestrogen or progesterone receptor status and disease-free interval in breast cancer patients.
Supporting Evidence
- 62.6% of patients were oestrogen receptor positive.
- 62.9% of patients were progesterone receptor positive.
- Only 1.9% of patients received postoperative endocrine treatment.
Takeaway
The study looked at women with breast cancer and found that having certain hormone receptors didn't help predict how long they would be free of disease after treatment.
Methodology
Receptor assays were performed on tumor samples from 286 women, with follow-up for at least 24 months.
Potential Biases
Potential bias due to the retrospective nature of some data and the influence of adjuvant treatments.
Limitations
The study had a small percentage of patients receiving adjuvant treatment, which may affect the results.
Participant Demographics
30% pre-menopausal and 70% postmenopausal women.
Want to read the original?
Access the complete publication on the publisher's website