Risk Factors for Cervical Intraepithelial Neoplasia in Japan
Author Information
Author(s): Yoshikawa H, Nagata C, Noda K, Nozawa S, Yajima A, Sekiya S, Sugimori H, Hirai Y, Kanazawa K, Sugase M, Shimizu H, Kawana T
Primary Institution: Department of Obstetrics and Gynecology, University of Tokyo
Hypothesis
What are the risk factors for cervical intraepithelial neoplasia in Japan?
Conclusion
The study found that after accounting for human papillomavirus infection, being married, having an early age at first pregnancy, and multiparity were significant risk factors for cervical intraepithelial neoplasia.
Supporting Evidence
- CIN cases showed evidence of nine known risk factors including smoking and sexual behaviour.
- After adjustment for papillomavirus infection, the only remaining risk factors were being married, early age at first pregnancy, and multiparity.
Takeaway
This study looked at what causes a certain type of cervical cell change in women in Japan and found that being married and having children early are important factors.
Methodology
A case-control study was conducted with 167 pairs of cervical intra-epithelial neoplasia cases and controls.
Participant Demographics
Participants were women in Japan with cervical intra-epithelial neoplasia.
Digital Object Identifier (DOI)
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