Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
1997
Vertical Transmission of Herpes Simplex Virus in Pregnancy
publication
Evidence: low
Author Information
Author(s): G.M. Joffe, K. Olson, T.L. Merlin, A. Brown
Primary Institution: Love/ace Medical Center, Albuquerque, NM
Hypothesis
Does primary herpes infection in the second trimester lead to vertical transmission and severe neonatal outcomes?
Conclusion
Primary herpes infection in the second trimester can result in significant neonatal morbidity.
Supporting Evidence
- Herpes simplex virus infection has increased among women of reproductive age.
- Vertical transmission of HSV can lead to severe neonatal outcomes.
- Treatment recommendations for primary herpes in pregnancy are lacking.
Takeaway
If a pregnant woman gets herpes early on, it can make her babies very sick.
Methodology
Case report of a pregnant woman with primary herpes infection and subsequent neonatal outcomes.
Limitations
No randomized clinical trials exist to support treatment recommendations for herpes in pregnancy.
Participant Demographics
26-year-old woman, gravida 3, para 0, carrying dichorionic twins.
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