Recurrent Colonization of Women with Staphylococcus saprophyticus
Author Information
Author(s): M.E. Rupp, J. Han, R.V. Goering
Primary Institution: University of Nebraska Medical Center
Hypothesis
Is the colonization of Staphylococcus saprophyticus persistent or recurrent in women?
Conclusion
Women with repeated recovery of Staphylococcus saprophyticus from their urogenital tracts experience recurrent colonization with different strains.
Supporting Evidence
- All isolates of S. saprophyticus from the study subjects were classified as genetically unique.
- Subjects experienced recurrent colonization with different isolates of S. saprophyticus.
- None of the women had urinary-tract symptoms or experienced a UTI during the study period.
Takeaway
Some women can get the same bacteria back in their bodies, but it's usually a different type each time.
Methodology
Genotypic typing of paired isolates of S. saprophyticus using plasmid fingerprinting and chromosomal-DNA restriction fragment-length polymorphism.
Potential Biases
A sampling error cannot be excluded as only single colonies were evaluated.
Limitations
The study had a small sample size and did not include symptomatic UTIs, which may affect the conclusions.
Participant Demographics
Average age of participants was 29 years; 2 were black and 1 was white.
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