GENDER DIFFERENCES IN MUSCLE STRENGTH AND TISSUE ASYMMETRY CHANGES OVER FIVE YEARS AMONG OLDER ADULTS
2024

Gender Differences in Muscle Strength and Tissue Asymmetry Changes Over Five Years Among Older Adults

Sample size: 3156 publication Evidence: moderate

Author Information

Author(s): Chang (Gudjonsson), Marco Recenti, Carlo Ricciardi, Alfonso Maria Ponsiglione, Francesco Amato, Magnus Kjartan Gislason, Paolo Gargiulo

Primary Institution: Landspitali University Hospital

Hypothesis

The study investigates whether the decline in muscle strength over a 5-year period correlates with changes in tissue asymmetry and explores potential gender differences between men and women.

Conclusion

Gender-specific variations in asymmetry parameters highlight how fat and muscle composition in men uniquely contribute to leg strength changes over time.

Supporting Evidence

  • The study involved a large sample size of 3,156 participants.
  • Changes in leg strength were significantly associated with tissue asymmetry in men.
  • In women, associations were observed with increased asymmetry parameters involving fat, muscle, and connective tissue.

Takeaway

As people get older, men and women experience different changes in muscle strength and tissue balance, which can affect their health.

Methodology

The longitudinal study assessed tissue asymmetry through CT scans and analyzed changes in leg strength and asymmetry parameters over 5 years using linear regression.

Participant Demographics

The study included 1,150 men and 1,587 women with a baseline mean age of 74.9, residing in Reykjavik, Iceland.

Statistical Information

P-Value

p<0.03

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2821

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