Molecular xenomonitoring of Schistosoma mansoni infections in Biomphalaria choanomphala at Lake Victoria, East Africa: Assessing roles of abiotic and biotic factors
2025

Molecular Monitoring of Schistosoma mansoni Infections in Lake Victoria Snails

Sample size: 170 publication 10 minutes Evidence: moderate

Author Information

Author(s): Andrus Peter S., Standley Claire J., Stothard J. Russell, Wade Christopher M.

Primary Institution: School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

Hypothesis

What abiotic and biotic factors influence the prevalence of Schistosoma mansoni infection in Biomphalaria choanomphala snails at Lake Victoria?

Conclusion

The study found a mean prevalence of Schistosoma mansoni infection of 9.3% in Biomphalaria choanomphala snails, with significant relationships between infection prevalence and various environmental factors.

Supporting Evidence

  • The overall mean prevalence of S. mansoni infection at Lake Victoria was 9.3%.
  • The highest prevalence of infection occurred on the Tanzanian shoreline (13.1%).
  • A significant positive relationship was found between S. mansoni infection and higher levels of Biomphalaria choanomphala abundance.
  • Sites with S. mansoni infection had a higher mean haplotype diversity score compared to sites without infection.

Takeaway

Researchers looked at snails in Lake Victoria to see how many had a parasite that can make people sick, finding that 9 out of every 100 snails were infected.

Methodology

The study used molecular xenomonitoring to assess the prevalence of S. mansoni infection in snail populations across different shorelines of Lake Victoria, analyzing various abiotic and biotic factors.

Potential Biases

Potential biases may arise from the opportunistic selection of sampling sites and the reliance on molecular methods for infection detection.

Limitations

The study is based on archival data and may not account for all environmental or human-related factors influencing infection rates.

Participant Demographics

The study focused on Biomphalaria choanomphala snails collected from the Kenyan, Tanzanian, and Ugandan shorelines of Lake Victoria.

Statistical Information

P-Value

p=0.215

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pntd.0012771

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