Echocardiographic assessment of pulmonary artery occlusion pressure in ventilated patients: a transoesophageal study
2008

Echocardiographic Assessment of Pulmonary Artery Pressure in Ventilated Patients

Sample size: 88 publication 10 minutes Evidence: high

Author Information

Author(s): Philippe Vignon, Ali AitHssain, Bruno François, Pierre-Marie Preux, Nicolas Pichon, Marc Clavel, Jean-Pierre Frat, Hervé Gastinne

Primary Institution: Dupuytren Teaching Hospital

Hypothesis

Can transoesophageal echocardiography (TEE) Doppler accurately predict invasive pulmonary artery occlusion pressure (PAOP) ≤ 18 mmHg in ventilated patients?

Conclusion

TEE accurately predicts invasive PAOP ≤ 18 mmHg in ventilated patients, enhancing its diagnostic value for those with suspected acute lung injury or acute respiratory distress syndrome.

Supporting Evidence

  • Mitral E/A ≤ 1.4, pulmonary vein S/D > 0.65, and systolic fraction > 44% best predicted an invasive PAOP ≤ 18 mmHg.
  • Lateral E/E' ≤ 8.0 or E/Vp ≤ 1.7 predicted a PAOP ≤ 18 mmHg with high sensitivity and specificity.
  • The study included 88 ventilated patients, with 70 having PAOP ≤ 18 mmHg.

Takeaway

Doctors can use a special ultrasound test called TEE to see if a patient's heart is under too much pressure, which helps them treat breathing problems better.

Methodology

The study compared TEE Doppler parameters to invasive PAOP measurements in 88 ventilated patients over two protocols.

Potential Biases

Potential bias due to the study's design and the exclusion of certain patient groups.

Limitations

The study's reliance on invasive PAOP measurements, which have known limitations, and the exclusion of patients with non-sinus rhythm or significant valvulopathy.

Participant Demographics

Mean age 63 ± 14 years; 59 men; 72% receiving vasopressor therapy.

Statistical Information

P-Value

0.53

Confidence Interval

95% CI: 0.70–0.92

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc6792

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