Metabolic Syndrome in Vietnamese Women with Early Rheumatoid Arthritis
Author Information
Author(s): Dao Hanh-Hung, Do Quan-Trung, Sakamoto Junichi
Primary Institution: Bach Mai University Hospital
Hypothesis
The study aimed to identify the prevalence of metabolic syndrome (MetS) and determine the potential factors associated with its presence in Vietnamese women with early rheumatoid arthritis.
Conclusion
Women with early rheumatoid arthritis have a higher prevalence of metabolic syndrome compared to healthy controls, with certain inflammatory markers and less methotrexate use being significant predictors.
Supporting Evidence
- Prevalence of metabolic syndrome in women with RA ranged from 16.2% to 40.9%.
- Women with RA had higher rates of hypertension and low HDL-C levels compared to controls.
- Less methotrexate use was associated with the presence of metabolic syndrome.
Takeaway
This study found that women with early rheumatoid arthritis are more likely to have metabolic syndrome, which can lead to heart problems. Doctors should check for this condition in these patients.
Methodology
A cross-sectional study comparing 105 women with early rheumatoid arthritis to 105 age-matched healthy controls, assessing metabolic syndrome using various definitions.
Potential Biases
Potential selection bias due to the study being conducted at a tertiary referral center.
Limitations
The study was limited to women and had a small sample size, which may not represent the entire population of rheumatoid arthritis patients.
Participant Demographics
105 Vietnamese women with early rheumatoid arthritis aged 26 to 73 years.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.073 to 3.195
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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