Impact of Liver Cirrhosis Type on Cognitive Function and Quality of Life
Author Information
Author(s): Kalaitzakis Evangelos, Josefsson Axel, Björnsson Einar
Primary Institution: Sahlgrenska University Hospital
Hypothesis
Does the type or etiology of liver cirrhosis relate to the presence of hepatic encephalopathy or health-related quality of life?
Conclusion
Cirrhosis etiology does not seem to be related to hepatic encephalopathy or health-related quality of life.
Supporting Evidence
- Diabetes mellitus was more common in patients with hepatocellular cirrhosis compared to cholestatic cirrhosis.
- The prevalence of hepatic encephalopathy did not differ significantly among different cirrhosis etiologies.
- Health-related quality of life was negatively impacted by the presence of hepatic encephalopathy.
Takeaway
This study found that the type of liver cirrhosis doesn't change how patients feel about their health or their mental function.
Methodology
156 cirrhotic patients were evaluated for hepatic encephalopathy and quality of life using psychometric tests and questionnaires.
Potential Biases
Potential selection bias as patients with certain conditions were excluded.
Limitations
The study is cross-sectional, which limits the ability to establish cause-effect relationships.
Participant Demographics
Patients included both genders with a mean age of 56 years; 127 had hepatocellular cirrhosis and 29 had cholestatic cirrhosis.
Statistical Information
Statistical Significance
p > 0.05
Digital Object Identifier (DOI)
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