Gastric Cancer and Bracken Exposure in Gwynedd
Author Information
Author(s): O.P. Galpin, C.J. Whitaker, Rh. Whitaker, J.Y. Kassab
Primary Institution: Ysbyty Gwynedd Hospital; Centre for Applied Statistics, University College of North Wales
Hypothesis
Is there a link between bracken exposure in childhood and the risk of gastric cancer?
Conclusion
Exposure to bracken in childhood is associated with an increased risk of gastric cancer.
Supporting Evidence
- Bracken exposure in childhood had a relative risk of 2.34 compared to non-cancer controls.
- Length of residence in Gwynedd was associated with increased risk, reaching a relative risk of 2.46 for over 60 years.
- Consumption of buttermilk in adulthood was significantly associated with increased risk of gastric cancer.
Takeaway
Kids who grew up around bracken plants might have a higher chance of getting stomach cancer when they grow up.
Methodology
The study matched 101 gastric cancer patients with non-cancer controls based on age, sex, and social class, using questionnaires to assess bracken exposure and other factors.
Potential Biases
Potential selection bias in matching cases and controls.
Limitations
The study relied on self-reported data, which may be subject to recall bias.
Participant Demographics
Participants were residents of Gwynedd, aged 30-88 years, matched by sex, age, and social class.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
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