Anti-microbial drug utilization in patients of febrile neutropenia on cancer chemotherapy
2008

Anti-microbial Drug Use in Cancer Patients with Febrile Neutropenia

Sample size: 211 publication Evidence: moderate

Author Information

Author(s): Saxena D, Roy V, Bahadur A K, Mishra B

Primary Institution: Maulana Azad Medical College and Loknayak Hospital

Hypothesis

The study aims to assess the pattern of use of antimicrobial agents in patients with febrile neutropenia undergoing chemotherapy.

Conclusion

The selection of antimicrobial agents does not appear to be based on specific patient factors, risk category, or antibiotic sensitivity pattern.

Supporting Evidence

  • The incidence of febrile neutropenia in the hospital was 13.3%.
  • The average antimicrobial exposure was 4.16 days per patient.
  • A total of 8 antimicrobial agents were used in the study.

Takeaway

Doctors need to be careful about the antibiotics they use for cancer patients with fever, as using the wrong ones can lead to more problems.

Methodology

An observational, prospective cohort study was conducted assessing patients with febrile neutropenia for antimicrobial use.

Potential Biases

Potential bias in antibiotic selection due to lack of adherence to guidelines.

Limitations

The study may not reflect practices outside the specific hospital setting.

Participant Demographics

Majority of patients were low risk (98.1%) and suffering from cancer.

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