Multicentre evaluation of the Monarch (IL) clinical chemistry analyser
1989

Evaluation of the Monarch Clinical Chemistry Analyser

Sample size: 3 publication Evidence: moderate

Author Information

Author(s): Ferruccio Ceriotti, Emma Guagnellini, Francesco Zoppi, Norberto Montalbetti, Carlo Okely, Pierangelo Bonini

Primary Institution: Istituto Scientifwo H. S. Raffaele

Hypothesis

The Monarch analyser's performance was evaluated for precision, linearity, and accuracy compared to routine methods.

Conclusion

The Monarch analyser demonstrated good reliability and is now used as the routine clinical chemistry analyser in two of the three participating laboratories.

Supporting Evidence

  • The Monarch showed excellent photometric and dispensing accuracy.
  • Calibration stability was good for most analytes.
  • Overall precision was acceptable for the majority of analytes tested.

Takeaway

The Monarch analyser is a machine that helps test blood samples accurately and is now trusted by doctors in two hospitals.

Methodology

The evaluation involved comparing the Monarch analyser's performance with routine methods across three different laboratories.

Potential Biases

Some method-to-method carry-over was observed, particularly when total protein determination was followed by urate measurement.

Limitations

Not all experiments could be performed in each laboratory due to practical and organizational reasons.

Participant Demographics

Laboratories involved in the evaluation were from different locations, including Istituto Scientifwo H. S. Raffaele and Ospedale Bassini.

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