Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients
Author Information
Author(s): I. L. G. Farias, M. C. S. Araújo, J. G. Farias, L. V. Rossato, L. I. Elsenbach, S. L. Dalmora, N. M. P. Flores, M. Durigon, I. B. M. Cruz, V. M. Morsch, M. R. C. Schetinger
Primary Institution: Universidade Federal de Santa Maria
Hypothesis
Can Uncaria tomentosa minimize the side effects of chemotherapy and improve antioxidant status in colorectal cancer patients?
Conclusion
Uncaria tomentosa did not effectively reduce the side effects of chemotherapy in colorectal cancer patients.
Supporting Evidence
- The study involved 43 colorectal cancer patients undergoing chemotherapy.
- Patients were divided into two groups: one received chemotherapy plus Uncaria tomentosa, and the other received chemotherapy alone.
- No significant differences were found in blood parameters between the two groups.
Takeaway
This study tested a plant called Uncaria tomentosa to see if it could help people with cancer feel better during chemotherapy, but it didn't work.
Methodology
A randomized clinical trial with 43 colorectal cancer patients receiving either chemotherapy alone or chemotherapy plus Uncaria tomentosa.
Limitations
The study did not find significant differences in hematological parameters or oxidative stress between the groups.
Participant Demographics
43 patients (26 female, 17 male) with colorectal cancer undergoing chemotherapy.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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