The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a randomized clinical trial
2024

Kava for Helping Smokers Quit

Sample size: 76 publication Evidence: moderate

Author Information

Author(s): Xing Chengguo, Malaty John, Malham Melissa Bou, Orlando Frank A., Lynch Allison, Huo Zhiguang, François Magda, Firpi-Morell Roberto, Fisher Carla L., Christou Demetra D., Salloum Ramzi G.

Primary Institution: University of Florida

Hypothesis

AB-free kava is a novel and promising intervention to facilitate tobacco cessation via its holistic effects associated with managing stress and insomnia during abstinence.

Conclusion

The study aims to evaluate the effects of AB-free kava on smoking cessation, stress, and sleep among smokers.

Supporting Evidence

  • Kava has historical usage for its relaxing effects and ability to enhance sleep.
  • Preliminary studies suggest kava may reduce tobacco dependence and improve biomarkers related to stress and sleep.
  • The study aims to replicate previous findings on kava's effects on biological signatures associated with tobacco use.

Takeaway

This study is testing if a special type of kava can help people stop smoking by making them feel less stressed and helping them sleep better.

Methodology

A double-blind randomized placebo-controlled trial will enroll 76 smokers who will consume AB-free kava or placebo for 4 weeks.

Limitations

The study may have limitations related to participant adherence and the generalizability of findings to broader populations.

Participant Demographics

Participants are active smokers intending to quit, with a focus on those who smoke at least 10 cigarettes per day.

Digital Object Identifier (DOI)

10.1186/s12906-024-04722-9

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