Multi-locus sequence analysis of mycoplasma capricolum subsp. capripneumoniae for the molecular epidemiology of contagious caprine pleuropneumonia
2011

Molecular Epidemiology of Contagious Caprine Pleuropneumonia

Sample size: 25 publication Evidence: high

Author Information

Author(s): Manso-Silván Lucía, Dupuy Virginie, Chu Yuefeng, Thiaucourt François

Primary Institution: CIRAD, UMR CMAEE, Montpellier, France

Hypothesis

The study aims to determine whether recently identified cases of Mycoplasma capricolum subsp. capripneumoniae in continental Asia were due to recent importation or if they were endemic to the region.

Conclusion

The study concludes that contagious caprine pleuropneumonia has likely been endemic in continental Asia for a long time, rather than being recently imported.

Supporting Evidence

  • The study identified 15 sequence types among 25 strains based on 53 polymorphic positions.
  • Two evolutionary lineages comprising five groups were revealed, correlating with geographic origins.
  • A distinct Asian cluster was found, indicating local evolution rather than recent importation.

Takeaway

This study looks at a disease in goats and finds that it has probably been around in Asia for a long time, not just recently brought there.

Methodology

The study used Multi-Locus Sequence Analysis (MLSA) to analyze 25 strains of Mycoplasma capricolum subsp. capripneumoniae.

Limitations

The main limitation is the lack of Mccp strains or DNA samples for analysis.

Digital Object Identifier (DOI)

10.1186/1297-9716-42-86

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