Neutrophil-to-Lymphocyte Ratio Predicts Outcomes After Stroke Treatment
Author Information
Author(s): Gao Weiwei, Annadurdyyev Arslan, Yu Lingfeng, Huang Rong, Liu Bin, Lin Yixiong, Li Huaiyi, Zhu Renjing
Primary Institution: Zhongshan Hospital of Xiamen University
Hypothesis
Dynamic changes in neutrophil-to-lymphocyte ratio (NLR) and its derived indices can predict 90-day outcomes in acute ischemic stroke patients after mechanical thrombectomy.
Conclusion
Inflammatory markers on day 3 post-mechanical thrombectomy can independently predict prognosis in acute ischemic stroke patients.
Supporting Evidence
- NLR, dNLR, and NMLR levels were higher in patients with poor outcomes.
- Dynamic monitoring of inflammatory markers may help in risk stratification.
- Each unit increase in NLR was associated with a 38% increased risk of poor outcomes.
- Day 3 NLR had an AUC of 0.85 for predicting poor outcomes.
Takeaway
Doctors can check certain blood markers after stroke treatment to see how well a patient might do in the next few months.
Methodology
This was a single-center retrospective cohort study analyzing blood samples from stroke patients at three time points after treatment.
Potential Biases
Selection bias may occur due to the exclusion of patients with incomplete data or early death.
Limitations
The study is limited by its single-center design and potential selection bias due to exclusion criteria.
Participant Demographics
Median age was 68 years, with 66.43% male participants.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.28–1.49
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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