Potential Urine Biomarkers for COVID-19 Diagnosis and Prognosis
Author Information
Author(s): Jennifer Narro-Serrano, Frutos Carlos Marhuenda-Egea
Primary Institution: University of Alicante
Hypothesis
Can urine biomarkers provide insights into the diagnosis, severity, and prognosis of COVID-19?
Conclusion
Urinary biomarkers can help diagnose COVID-19 and assess its severity and prognosis.
Supporting Evidence
- Urine is a non-invasive sample that can be collected frequently for biomarker analysis.
- Identified biomarkers include kynurenine, neopterin, and ACE2, which reflect disease severity.
- Urinary biomarkers can provide insights into metabolic stress and renal dysfunction in COVID-19 patients.
- Standardized protocols are needed to improve the reliability of urine-based diagnostics.
Takeaway
Scientists are looking at urine to find clues about COVID-19, which can help doctors know how sick someone is and how to treat them.
Methodology
This review analyzed 45 studies on urine biomarkers for COVID-19 using various omics and clinical analyses.
Potential Biases
Many studies focused on specific cohorts, limiting generalizability to broader populations.
Limitations
The studies varied widely in methodologies and sample sizes, which complicates direct comparisons.
Participant Demographics
The studies included diverse populations, but many were hospitalized or critically ill patients.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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