Mutant Oncogenes. Targets for Therapy
1992

Mutant Oncogenes: Targets for Therapy

publication

Author Information

Author(s): N. Lemoine, A. Epenetos

Conclusion

The book presents promising potential for oncogenes and their products as targets for specific cancer therapies.

Supporting Evidence

  • Many papers in the book highlight the potential of oncogenes as therapy targets.
  • Monoclonal antibodies against c-erbB-2 show promise in treating cancers with this receptor.
  • Strategies involving antibodies to c-erbB-2 coupled with toxins are discussed.
  • The book provides an overview of ras oncogenes and their clinical potentials.
  • Potential strategies for reverting ras transformation are outlined.

Takeaway

This book talks about how certain genes can be used to help treat cancer, which is really exciting!

Limitations

Some papers only describe findings without focusing on therapy targets, and the coverage of tumor suppressor genes is limited.

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