Identifying geographic areas with high disease rates: when do confidence intervals for rates and a disease cluster detection method agree?
2006

Comparing Disease Rate Detection Methods

Sample size: 17 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rhonda J Rosychuk

Primary Institution: University of Alberta

Hypothesis

When do confidence intervals for disease rates and a disease cluster detection method agree?

Conclusion

The cluster detection method is preferred when the cluster size exceeds the number of cases in an administrative area or when the expected number of cases exceeds a threshold.

Supporting Evidence

  • Two areas were significant with both methods and one additional area was identified with the cluster detection method.
  • The overall provincial rate was 105.3 cases per 100,000 population.
  • Cells with confidence intervals above the overall rate were classified as areas of high rates.

Takeaway

Researchers looked at how to find areas with high disease rates and found that different methods can give similar results, but sometimes they don't agree.

Methodology

The study compared the Besag and Newell cluster detection method with confidence intervals for disease rates using a dataset on self-inflicted injuries.

Limitations

The methods may yield different results depending on the cluster size and the number of cases.

Participant Demographics

The analysis focused on the pediatric population under 18 years old.

Statistical Information

P-Value

0.026

Confidence Interval

(0.0009, 0.0016)

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-072X-5-46

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