High Levels of Antimicrobial Resistance in Trauma Care
Author Information
Author(s): Behera Bijayini, Mathur Purva
Primary Institution: All India Institute of Medical Sciences
Hypothesis
What is the antimicrobial susceptibility profile of pathogens in trauma patients at a tertiary care center in India?
Conclusion
The study found a high prevalence of multi-drug resistant Gram-negative bacteria and Candida spp. at the trauma care center.
Supporting Evidence
- 30% of samples were culture positive for one or more organisms.
- P. aeruginosa was the most common isolate, followed by Candida spp.
- 87% of Gram-negative bacteria tested positive for ESBL production.
- 246 isolates were resistant to all five major classes of antimicrobials.
- 52% of carbapenem-resistant isolates produced metallo β-lactamase.
Takeaway
Infections in trauma patients are very serious, and many germs are resistant to common antibiotics, making treatment difficult.
Methodology
A retrospective study reviewing nosocomial infections and antimicrobial susceptibility of pathogens using standard microbiological techniques.
Limitations
The study is limited to a single center and may not represent broader trends.
Participant Demographics
Patients at a level-1 trauma care center in India.
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