Minimally invasive treatments for benign prostatic enlargement: systematic review of randomised controlled trials
2008

Minimally Invasive Treatments for Benign Prostatic Enlargement

Sample size: 2434 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lourenco Tania, Pickard Robert, Vale Luke, Grant Adrian, Fraser Cynthia, MacLennan Graeme, N’Dow James

Primary Institution: University of Aberdeen

Hypothesis

To compare the effectiveness and risk profile of minimally invasive interventions against the current standard of transurethral resection of the prostate.

Conclusion

Minimally invasive interventions are less effective than transurethral resection of the prostate but have a better risk profile with fewer adverse events.

Supporting Evidence

  • Minimally invasive treatments showed less improvement in symptom scores compared to transurethral resection.
  • Rates of reoperation were significantly higher for minimally invasive treatments.
  • Minimally invasive interventions had fewer adverse events than transurethral resection.

Takeaway

This study looked at different ways to treat prostate enlargement. Some new methods are easier on the body but don't work as well as the old method.

Methodology

Systematic review and meta-analysis of randomised controlled trials.

Potential Biases

Potential publication bias due to exclusion of unpublished reports.

Limitations

Many studies had small sample sizes and poor quality, and some did not report key data.

Participant Demographics

Participants were men with benign prostatic enlargement, average age around 67 years.

Statistical Information

P-Value

0.004

Confidence Interval

1.27 to 6.53

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1136/bmj.a1662

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication