Nutritional Status and Survival in Ovarian Cancer
Author Information
Author(s): Gupta Digant, Lammersfeld Carolyn A, Vashi Pankaj G, Dahlk Sadie L, Lis Christopher G
Primary Institution: Cancer Treatment Centers of America® (CTCA) at Midwestern Regional Medical Center
Hypothesis
Can subjective global assessment of nutritional status predict survival in ovarian cancer?
Conclusion
Low SGA scores are associated with better survival outcomes in ovarian cancer patients.
Supporting Evidence
- Well nourished patients had a median survival of 19.3 months.
- Moderately malnourished patients had a median survival of 15.5 months.
- Severely malnourished patients had a median survival of 6.7 months.
- Moderately malnourished status was associated with a relative risk of 2.1 compared to well nourished status.
- Severely malnourished status was associated with a relative risk of 3.4 compared to well nourished status.
Takeaway
This study found that how well-nourished ovarian cancer patients are can help predict how long they might live.
Methodology
A retrospective chart review of 132 ovarian cancer patients was conducted, using Subjective Global Assessment to classify nutritional status and analyze survival data.
Potential Biases
Observer bias may affect the accuracy of the SGA due to its subjective nature.
Limitations
The study's retrospective nature may limit the accuracy of survival time calculations, and it did not evaluate the effectiveness of nutritional interventions.
Participant Demographics
Median age was 54.4 years, with a range from 25.5 to 82.5 years; 66 patients were well-nourished, 35 moderately malnourished, and 31 severely malnourished.
Statistical Information
P-Value
0.0003
Confidence Interval
95% CI: 14.1 to 24.5
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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