Organic Papers(S)-1-(2-Chlorophenyl)-2-oxocyclohexan-1-aminium d-tartrate
2011
Characterization of S-Norketamine D-Tartrate Salt
publication
Evidence: high
Author Information
Author(s): Hojahmat Marhaba, Zheng Guangrong, Max Siegler, Sean Parkin, Manfred Biermann, Peter A. Crooks
Primary Institution: Yaupon Therapeutics, Inc.
Hypothesis
To confirm the absolute configuration of (+)-norketamine.
Conclusion
The study successfully characterized the crystalline structure of S-norketamine D-tartrate salt.
Supporting Evidence
- S-Ketamine is more potent as an anesthetic than its R-enantiomer.
- S-Norketamine is emerging as a novel drug for treating neuropathic pain.
Takeaway
The researchers looked at a special form of a drug called S-norketamine to understand its structure better.
Methodology
X-ray crystallographic characterization was used to analyze the structure.
Digital Object Identifier (DOI)
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