Recent Advances in Autoimmune Encephalitis
Author Information
Author(s): João Henrique Fregadolli Ferreira, Caio César Diniz Disserol, Bruna de Freitas Dias, Alexandre Coelho Marques, Marina Driemeier Cardoso, Pedro Victor de Castro Silva, Fabio Fieni Toso, Lívia Almeida Dutra
Primary Institution: Hospital Israelita Albert Einstein, Instituto do Cérebro, São Paulo SP, Brazil
Conclusion
The review highlights significant advancements in understanding autoimmune encephalitis, including its pathophysiology, genetic factors, and diagnostic challenges.
Supporting Evidence
- Autoimmune encephalitis is a rare disease with an annual incidence of 1.2 cases per 100,000 inhabitants.
- More than 12 clinical syndromes and antibodies related to autoimmune encephalitis have been identified since 2007.
- Genetic studies have shown associations with human leukocyte antigens for various types of autoimmune encephalitis.
Takeaway
Autoimmune encephalitis is a brain condition caused by the body's immune system attacking its own cells, and researchers are learning more about how it works and how to diagnose it better.
Methodology
The article reviews recent studies and findings related to autoimmune encephalitis, focusing on pathophysiology, genetics, diagnosis, and treatment.
Limitations
The review discusses limitations of commercial assays for diagnosis and the challenges in accurately diagnosing autoimmune encephalitis.
Digital Object Identifier (DOI)
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