The incidence and nature of in-hospital adverse events: a systematic review
2008

Understanding In-Hospital Adverse Events

Sample size: 74485 publication Evidence: moderate

Author Information

Author(s): de Vries E N, Ramrattan M A, Smorenburg S M, Gouma D J, Boermeester M A

Primary Institution: Academic Medical Centre, University of Amsterdam

Hypothesis

What percentage of in-hospital adverse events are preventable and what types are most common?

Conclusion

Nearly 9% of patients experience adverse events during hospital admission, with a significant portion being preventable.

Supporting Evidence

  • The median overall incidence of in-hospital adverse events was found to be 9.2%.
  • 43.5% of the adverse events were judged to be preventable.
  • 56.3% of patients experienced no or minor disability from adverse events.
  • Operation-related events accounted for 39.6% of adverse events.
  • Medication-related events constituted 15.1% of adverse events.

Takeaway

When people go to the hospital, about 1 in 10 might have a problem caused by the hospital itself, and many of these problems could be avoided.

Methodology

A systematic review of literature was conducted, analyzing data from multiple studies on in-hospital adverse events.

Potential Biases

Differences in methodology and perspectives among studies may lead to varying incidence rates.

Limitations

The review is based solely on retrospective record studies, which may underestimate the problem due to documentation quality issues.

Participant Demographics

The studies included adult hospital patients from various countries including the USA, Canada, UK, Australia, and New Zealand.

Statistical Information

Confidence Interval

9.2% (IQR 4.6–12.4%) for incidence, 43.5% (IQR 39.4–49.6%) for preventability

Digital Object Identifier (DOI)

10.1136/qshc.2007.023622

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