Leiomyosarcoma of the Prostate: Case Report and Review of 54 Previously Published Cases
2008

Case Report of Prostate Leiomyosarcoma

Sample size: 55 publication Evidence: moderate

Author Information

Author(s): Gerasimos P. Vandoros, Theodoros Manolidis, Michalis V. Karamouzis, Maria Gkermpesi, Maria Lambropoulou, Athanasios G. Papatsoris, Ioannis Zachos, Panagiotis A. Konstantinopoulos

Primary Institution: Aeghion General Hospital

Conclusion

Prostate leiomyosarcoma is a rare and aggressive cancer with a median survival of 17 months.

Supporting Evidence

  • Prostate leiomyosarcoma accounts for less than 0.1% of primary prostate malignancies.
  • Median survival for patients with metastatic disease at presentation was 5 months compared to 20 months for those without.
  • Patients with negative surgical margins had a median survival of 41 months compared to 13 months for those with positive margins.

Takeaway

Prostate leiomyosarcoma is a very rare type of cancer that usually grows quickly and can spread to other parts of the body.

Methodology

The study reviewed 54 previously published cases and included a case report of a patient with prostate leiomyosarcoma.

Limitations

The study is retrospective and relies on previously published data, which may have variability in reporting.

Participant Demographics

The median age of patients was 63.8 years, with a range from 40 to 80 years.

Statistical Information

P-Value

0.018

Confidence Interval

95% CI 20.7–43.7 months

Statistical Significance

p = .018

Digital Object Identifier (DOI)

10.1155/2008/458709

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