Functional Variation of SLC52A3 rs13042395 Predicts Survival of Chinese Gastric Cancer Patients
2024
Correction to Study on SLC52A3 and Gastric Cancer Survival
Sample size: 926
publication
Evidence: moderate
Author Information
Author(s): X. Qu, L. Cheng, L. Zhao, L. Qiu, W. Guo
Conclusion
The correction clarifies that the SLC52A3 rs13042395 C>T variation is significantly associated with poor survival in Chinese gastric cancer patients.
Supporting Evidence
- SLC52A3 rs13042395 C>T variation was significantly associated with poor survival in a cohort of 926 Chinese gastric cancer patients.
- Patients with the CC genotype had better survival compared to those with CT/TT genotypes.
- The genetic change was an independent predictor for worse survival after adjusting for clinical variables.
Takeaway
This study found that a specific genetic change can help predict how long gastric cancer patients in China might live.
Methodology
The study used multivariate Cox analysis to assess the impact of the SLC52A3 genetic variation on survival.
Participant Demographics
926 Chinese gastric cancer patients, including subgroups based on gender and smoking history.
Statistical Information
P-Value
0.046
Confidence Interval
1.00–1.48
Statistical Significance
p=0.046
Digital Object Identifier (DOI)
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