A case of radiation-induced sternal malignant fibrous histiocytoma treated with neoadjuvant chemotherapy and surgical resection
2008

Case of Radiation-Induced Sternal Malignant Fibrous Histiocytoma

Sample size: 1 publication Evidence: moderate

Author Information

Author(s): Kocer Bulent, Gulbahar Gultekin, Erdogan Bulent, Budakoglu Burcin, Erekul Selim, Dural Koray, Sakinci Unal

Primary Institution: Numune Education and Research Hospital, Ankara, Turkey

Hypothesis

Neoadjuvant chemotherapy can effectively reduce tumor size in cases of malignant fibrous histiocytoma (MFH) before surgical resection.

Conclusion

Neoadjuvant chemotherapy was effective in reducing the size of the tumor, allowing for successful surgical resection.

Supporting Evidence

  • Neoadjuvant chemotherapy reduced the tumor size from 5x6 cm to 3x3 cm.
  • The patient had a history of breast cancer and received radiotherapy 19 years prior.
  • Postoperative follow-up showed recurrence and cranial metastasis.

Takeaway

A woman with a rare tumor on her sternum got smaller after chemotherapy, which helped doctors remove it safely.

Methodology

The patient received neoadjuvant chemotherapy followed by surgical resection of the tumor.

Limitations

The patient experienced recurrence and later developed cranial metastasis, leading to her death.

Participant Demographics

50-year-old female patient with a history of breast cancer and radiotherapy.

Digital Object Identifier (DOI)

10.1186/1477-7819-6-138

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