Geographic and topographic determinants of local FMD transmission applied to the 2001 UK FMD epidemic
2008

Geographic Factors Affecting Foot and Mouth Disease Spread in the UK

Sample size: 301 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bessell Paul R, Shaw Darren J, Savill Nicholas J, Woolhouse Mark E J

Primary Institution: Centre for Infectious Diseases, School of Biological Sciences, University of Edinburgh

Hypothesis

How do geographical features influence the transmission of Foot and Mouth Disease during the 2001 UK epidemic?

Conclusion

The study found that rivers and railways act as barriers to the transmission of Foot and Mouth Disease, while other geographical features did not significantly impact transmission risk.

Supporting Evidence

  • Rivers and railways significantly reduce the risk of FMD transmission.
  • Other geographical features like roads and elevation change did not show a significant impact on transmission risk.
  • The study analyzed data from 113 infected farms and 188 control farms.

Takeaway

This study shows that rivers and railways can help stop the spread of a disease called Foot and Mouth Disease between farms.

Methodology

The study used a case-control design, matching 113 infected farms with 188 control farms based on geographical features and distance to the source of infection.

Potential Biases

Potential biases in source identification and the representativeness of the selected cases and controls.

Limitations

The analysis was limited to a small subset of infected premises and may not capture all geographical influences on transmission.

Participant Demographics

The study focused on farms in the UK affected by the 2001 FMD epidemic.

Statistical Information

P-Value

0.018

Confidence Interval

0.297, 0.887

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1746-6148-4-40

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