Normal pregnancy in a patient with β-thalassaemia major receiving iron chelation therapy with deferasirox (Exjade®)
2011
Normal Pregnancy in a Patient with β-Thalassaemia Major
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Vini Dimitra Servos, Philippos Drosou
Primary Institution: Thalassaemia Unit, Hospital of Nikaia, Athens, Greece
Hypothesis
Is deferasirox safe for use during pregnancy in patients with β-thalassaemia major?
Conclusion
The use of deferasirox during pregnancy was well tolerated and did not prevent the delivery of a healthy baby.
Supporting Evidence
- The patient had a successful pregnancy while on deferasirox.
- Deferasirox treatment was stopped upon confirmation of pregnancy.
- The baby was born healthy with normal weight and Apgar score.
Takeaway
A woman with a blood disorder had a healthy baby while taking a specific medication, but doctors usually don't recommend this medicine for pregnant women.
Methodology
Case study of a patient with β-thalassaemia major who became pregnant while receiving deferasirox.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
35-year-old female patient diagnosed with β-thalassaemia major.
Digital Object Identifier (DOI)
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