One-year outcome and quality of life of patients with subarachnoid hemorrhage admitted to intensive care unit: a single-center retrospective pilot study
2025

Long-term outcomes and quality of life in patients with subarachnoid hemorrhage

Sample size: 38 publication Evidence: moderate

Author Information

Author(s): Bergamini Carlo, Brogi Etrusca, Salvigni Sara, Castagnoli Diletta, Catucci Mattea, Gasperini Chiara, Cecchini Erica, Bevoni Moana, Bartoletti Sabina, Russo Maria, Faedo Serena, Pietrantozzi Dario, Passero Silvia, Romoli Michele, Bini Giovanni, Venditto Alessandra, Lafe Elvis, D’Andrea Marcello, Tosatto Luigino, Ruggiero Maria, Agnoletti Vanni, Russo Emanuele

Primary Institution: Bufalini Hospital, Azienda Unità Sanitaria Locale (AUSL) Della Romagna, Cesena, Italy

Hypothesis

What is the long-term outcome and quality of life for patients with subarachnoid hemorrhage admitted to the ICU?

Conclusion

The study found that high Hunt-Hess grades and early high intracranial pressure were related to unfavorable outcomes, while quality of life varied widely among patients with poor outcomes.

Supporting Evidence

  • Twenty-four patients (63.2%) had a favorable outcome (GOSE ≥ 4).
  • Among 29 patients (76.3%) who survived at 1 year, median EQ-5D Index was 0.743.
  • Median EQ-5D Index and median EQ-VAS were higher among patients with favorable outcomes.

Takeaway

This study looked at how patients do after having a serious brain bleed and found that some do well while others struggle, especially if they had certain complications.

Methodology

A single-center, observational, retrospective cohort study analyzing patients with non-traumatic subarachnoid hemorrhage admitted to the ICU.

Potential Biases

Potential bias due to the retrospective nature of the study and reliance on caregiver reports for quality of life assessments.

Limitations

The study has a small sample size and is limited to a single center, which may affect the generalizability of the results.

Participant Demographics

The cohort consisted of 63.2% females with a median age of 56 years.

Statistical Information

P-Value

p=0.037 for EQ-5D Index, p=0.003 for EQ-VAS

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/s44158-024-00223-w

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