Organic Papers
2011
Study of 2-Amino-3,4,5,6-tetrafluorobenzoic Acid
publication
Evidence: moderate
Author Information
Author(s): Liao Xiao-Jian, Guo Wei, Xu Shi-Hai
Primary Institution: Jinan University
Conclusion
The study successfully synthesized 2-Amino-3,4,5,6-tetrafluorobenzoic acid and characterized its crystal structure.
Supporting Evidence
- The compound was obtained as an intermediate in the synthesis of a coupling reagent.
- The asymmetric unit contains four independent and conformationally similar molecules.
- The molecules associate through various hydrogen bonds forming ribbon structures.
Takeaway
The researchers made a new chemical compound and looked at how its molecules are arranged in a crystal.
Methodology
The compound was synthesized using the Hofmann rearrangement and characterized using X-ray crystallography.
Digital Object Identifier (DOI)
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