Study of Aortic Pulse Wave Velocity and Vessel Wall Thickness in Hypertensive Patients
Author Information
Author(s): Brandts Anne, de Roos Albert, van Elderen Saskia G, Kroft Lucia J, Roes Stijntje D, Reiber Johan H, van der Geest Rob J, Westenberg Jos J
Primary Institution: Leiden University Medical Center
Hypothesis
There are associations between aortic and carotid wall thickness and aortic pulse wave velocity in subjects with and without hypertension.
Conclusion
MRI shows that aortic and carotid vessel wall thickness and aortic pulse wave velocity are higher in patients with hypertension compared to healthy volunteers.
Supporting Evidence
- Hypertensive patients had higher pulse wave velocity and vessel wall thickness compared to healthy volunteers.
- All measured parameters were significantly associated with age.
- The association between aortic pulse wave velocity and aortic vessel wall thickness was stronger than that with carotid vessel wall thickness.
Takeaway
This study looked at how thick the walls of blood vessels are and how fast blood moves through them in people with high blood pressure compared to healthy people.
Methodology
Fifteen hypertensive patients and fifteen matched healthy volunteers underwent MRI to assess pulse wave velocity and vessel wall thickness.
Participant Demographics
Fifteen patients (10 women, mean age 49±14 years) with hypertension and fifteen age- and gender-matched healthy volunteers.
Statistical Information
P-Value
0.011, <0.001, 0.014
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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