The Role of Genital Mycoplasmas in Pelvic Inflammatory Disease
Author Information
Author(s): Ashwin Chatwani, Ozgur H. Harmanli, Paul Nyirjesy, E. Albert Reece
Primary Institution: Temple University School of Medicine
Hypothesis
What is the role of Mycoplasma hominis and Ureaplasma urealyticum in pelvic inflammatory disease (PID)?
Conclusion
Genital mycoplasmas do not significantly affect the clinical presentation or course of PID.
Supporting Evidence
- Patients with and without genital mycoplasmas had similar clinical parameters.
- A significant percentage of patients continued to harbor genital mycoplasmas after PID resolution.
- Genital mycoplasmas do not seem to have a dominant pathogenic role in PID.
Takeaway
This study found that having certain germs in the body doesn't change how sick someone gets with PID, and some people can still have these germs even after they feel better.
Methodology
The study compared clinical and microbiologic variables in 114 patients with PID based on the isolation of M. hominis and U. urealyticum from their endometrial cavities.
Limitations
The study may not account for all potential confounding factors related to PID.
Participant Demographics
Patients with a clinical diagnosis of acute PID, average age around 25 years.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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