Critical limb ischaemia in a diabetic population from an Asian Centre: angiographic pattern of disease and 3-year limb salvage rate with percutaneous angioplasty as first line of treatment

2010

Angiographic Patterns and Limb Salvage Rates in Diabetic Patients with Critical Limb Ischemia

Sample size: 42 publication 10 minutes Evidence: moderate

Author Information

Author(s): Tan M, Pua U, Wong DES, Punamiya SJ, Chua GC, Teo N

Primary Institution: Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia

Hypothesis

What are the angiographic patterns of disease and the 3-year limb salvage rate in diabetic patients with critical limb ischemia treated with percutaneous angioplasty?

Conclusion

The 3-year limb salvage rates in Asian diabetics are lower than those in the western population, despite similar early limb salvage rates.

Supporting Evidence

Technical success was achieved in 90% of patients.
Limb salvage rates were 93% at 1 month and decreased to 66% at 3 years.
Mortality was 17% at 3 years, with deaths unrelated to limb issues.
91% of patients with rest pain had total symptom abolition.
66% of patients with gangrene showed healing after treatment.
All patients with non-healing ulcers showed documented healing after PTA.

Takeaway

This study looked at how well a treatment worked for people with diabetes who had serious leg problems. It found that while many people did well at first, fewer were able to keep their legs after three years compared to people in other countries.

Methodology

The study involved 42 diabetic patients who received percutaneous transluminal angioplasty and were followed for three years to assess limb salvage rates and angiographic patterns.