Molecular evolution and positive selection of the symbiotic gene NORK in Medicago truncatula
2007

Evolution of the NORK Gene in Medicago

Sample size: 32 publication Evidence: high

Author Information

Author(s): De Mita Stéphane, Santoni Sylvain, Ronfort Joëlle, Bataillon Thomas

Primary Institution: UMR 1097 Diversité et Adaptation des Plantes Cultivées – INRA Montpellier, France

Hypothesis

Is the evolution of the NORK gene influenced by changes in rhizobial specificity in Medicago?

Conclusion

Positive selection in the NORK gene does not correlate with changes in rhizobial specificity in the Medicago genus.

Supporting Evidence

  • The NORK gene is crucial for symbiotic interactions in legumes.
  • Positive selection was detected in the NORK gene across the Medicago genus.
  • Only one of five branches tested showed accelerated rates of amino acid substitutions.
  • The study involved sequencing a significant portion of the NORK gene in multiple species.

Takeaway

Scientists studied a gene called NORK in a group of plants called Medicago to see if its changes were linked to how these plants interact with bacteria. They found that the changes in the gene weren't related to the bacteria they worked with.

Methodology

Sequenced a 3610 nucleotide region of the NORK gene in 32 Medicago species and analyzed positive selection using codon substitution models.

Limitations

The study's findings may be affected by the phylogenetic tree used, which was based on a different locus.

Statistical Information

P-Value

< 10-12

Statistical Significance

p < 10-12

Digital Object Identifier (DOI)

10.1007/s00239-004-0367-2

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