Methyl 2-{[2,8-bis(trifluoromethyl)quinolin-4-yl]oxy}acetate
2011
Crystal Structure of Methyl 2-{[2,8-bis(trifluoromethyl)quinolin-4-yl]oxy}acetate
publication
Evidence: moderate
Author Information
Author(s): Feng Zhi-Qiang, Yang Xiao-Li, Ye Yuan-Feng, Wang Huai-Qing, Dong Tao
Primary Institution: School of Material Engineering, Jinling Institute of Technology, Nanjing, People’s Republic of China
Conclusion
The crystal structure of the compound shows effective stabilization through hydrogen bonds.
Supporting Evidence
- The compound is an important organic synthesis intermediate.
- The molecular structure shows a dihedral angle of 1.59° between the benzene and pyridyl rings.
- Hydrogen bonds create a three-dimensional network that stabilizes the crystal structure.
Takeaway
This study looks at the structure of a chemical compound that is important for making drugs, showing how its molecules stick together.
Methodology
The compound was prepared by dissolving it in ethanol and evaporating the solvent to obtain crystals.
Digital Object Identifier (DOI)
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