Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method
2011
Hydroxyapatite Formation on Polyurethane Nanofibers
publication
Evidence: moderate
Author Information
Author(s): Nirmala R, Nam Ki Taek, Navamathavan R, Park Soo-Jin, Kim Hak Yong
Primary Institution: Chonbuk National University
Hypothesis
The incorporation of calcium chloride (CaCl2) in polyurethane nanofibers enhances their bioactivity.
Conclusion
The study demonstrated that polyurethane nanofibers containing CaCl2 support the growth of apatite-like materials, enhancing their bioactive behavior.
Supporting Evidence
- The electrospun nanofibers exhibited a smooth surface and uniform diameters.
- Apatite-like materials formed on the nanofibers after incubation in simulated body fluid.
- The presence of CaCl2 improved the bioactivity of the polyurethane nanofibers.
Takeaway
This study shows that adding a salt called calcium chloride to special fibers can help them grow materials that are good for healing bones.
Methodology
Polyurethane nanofibers with varying concentrations of CaCl2 were created using electrospinning and tested for bioactivity in simulated body fluid.
Digital Object Identifier (DOI)
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