Rapidly evolving purpuric lesions to massive hemorrhagic bullae, with rapid improvement by Prednisolone: as a coetaneous manifestation of Systemic Lupus Erythematosus: a case report
2008

Rapidly evolving skin lesions in a lupus patient

Sample size: 1 publication Evidence: low

Author Information

Author(s): Khorvash Farzin, Naeini Alireza Emami, Behjati Mohaddeseh, Karimifar Mansoor, Khorvash Fariborz, Dialami Koorosh

Primary Institution: Isfahan University of Medical Sciences

Hypothesis

Can rapidly evolving purpuric lesions indicate systemic lupus erythematosus?

Conclusion

Rapidly evolving hemorrhagic bullae from primary purpuric lesions can occur in systemic lupus erythematosus and respond well to corticosteroid therapy.

Supporting Evidence

  • Patient presented with headache, vomiting, fever, and arthralgia.
  • Hemorrhagic ulcers and purpura were observed on admission.
  • Skin biopsy showed immune complex deposition in the dermoepidermal junction.
  • Patient responded well to corticosteroid therapy.

Takeaway

A 26-year-old woman had skin problems that got worse quickly, but she got better after taking a medicine called Prednisolone.

Methodology

Case report detailing clinical presentation, laboratory findings, and treatment response.

Limitations

Single case report limits generalizability of findings.

Participant Demographics

26-year-old female.

Digital Object Identifier (DOI)

10.1186/1757-1626-1-79

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