Feasibility and staff acceptability of implementing Xpert HIV-1 viral load point-of-care testing: a pilot study in San Francisco
2024

Feasibility of Point-of-Care HIV Viral Load Testing

Sample size: 113 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kelvin Moore Jr., Noelle Le Tourneau, Jasmin Alvarez, Santos Rodriguez, Janessa Broussard, Pierre-Cédric Crouch, Jorge Roman, Patricia Defechereux, Jason Bena, Kimberly A. Koester, Lissa Moran, Christopher Pilcher, Robert Grant, Katerina A. Christopoulos

Primary Institution: University of California, San Francisco

Hypothesis

Can point-of-care HIV viral load testing be feasibly implemented in a high-volume community sexual health clinic?

Conclusion

The study found that point-of-care HIV viral load testing is feasible and acceptable to staff, with results comparable to standard testing.

Supporting Evidence

  • The Xpert assay showed excellent agreement with COBAS testing.
  • Clinical staff found the Xpert testing acceptable for its rapid results.
  • Challenges included machine errors and staff workload concerns.
  • Testing could improve patient care by providing timely information.

Takeaway

This study shows that quick HIV tests can help doctors give better care to patients by providing fast results right at the clinic.

Methodology

A cross-sectional, mixed-methods study using remnant venipuncture specimens analyzed with the Xpert HIV-1 Viral Load assay.

Potential Biases

Potential biases related to staff workload and testing logistics were noted.

Limitations

The study's findings are based on a limited sample size and require validation with larger studies.

Participant Demographics

Participants were predominantly male (86.5%), non-white (55.8%), and mostly gay/lesbian/queer (89.2%), with a median age of 32.

Digital Object Identifier (DOI)

10.1186/s12879-024-10384-2

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