Effects of Chromium Histidinate on Obesity in Rats
Author Information
Author(s): Tuzcu Mehmet, Sahin Nurhan, Orhan Cemal, Agca Can Ali, Akdemir Fatih, Tuzcu Zeynep, Komorowski James, Sahin Kazim
Primary Institution: Firat University
Hypothesis
Does chromium histidinate supplementation affect obesity induced by a high-fat diet in rats?
Conclusion
Supplementation of chromium histidinate is protective against obesity in rats fed a high-fat diet.
Supporting Evidence
- Rats fed a high-fat diet had higher serum insulin and glucose levels compared to control rats.
- Supplementation with chromium histidinate increased liver chromium levels and decreased glucose levels in high-fat diet rats.
- Chromium histidinate reduced the expression of inflammatory markers in the liver.
Takeaway
This study found that giving chromium histidinate to rats on a high-fat diet helped them stay healthier and less overweight.
Methodology
Male Wistar rats were divided into four groups and fed different diets, with some receiving chromium histidinate supplementation.
Potential Biases
Potential bias due to funding from a company that sells chromium histidinate.
Limitations
The study was conducted only on rats, so results may not directly apply to humans.
Participant Demographics
Male Wistar rats, 8 weeks old.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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