Unusual Case of Acute Intestinal Obstruction
2010
Medication Induced Intestinal Obstruction
Sample size: 1
publication
Evidence: moderate
Author Information
Author(s): Manocha Divey, John Savio, Bansal Nidhi, Paul Manju
Primary Institution: SUNY Upstate Medical University
Hypothesis
Chronic NSAID use can cause diaphragm-like strictures within the bowel leading to intestinal obstruction.
Conclusion
The case illustrates that NSAID-related injury should be considered in patients with intestinal obstruction of unclear etiology.
Supporting Evidence
- Chronic NSAID use can lead to diaphragm disease, which causes intestinal obstructions.
- The patient had a significant history of long-term naproxen use.
- Histopathology showed mucosal ulceration and inflammation consistent with diaphragm disease.
Takeaway
Taking certain pain medications for a long time can cause problems in your belly, like blockages. In this case, a woman had to have surgery because of it.
Methodology
The patient underwent exploratory laparotomy and segmental resection of the ileum.
Limitations
Preoperative diagnosis of diaphragm disease is extremely difficult.
Participant Demographics
46 years old Caucasian female.
Digital Object Identifier (DOI)
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