2,2-Dimethyl-5-[(pyridin-2-ylamino)methylidene]-1,3-dioxane-4,6-dione
2011
2,2-Dimethyl-5-[(pyridin-2-ylamino)methylidene]-1,3-dioxane-4,6-dione
publication
Author Information
Author(s): Shi Jian-you, Li Jin-qi, Tong Rong-sheng, Lin He, Lu Chen
Primary Institution: Department of Pharmacy, Sichuan Academy of Medical Science and Sichuan Provincial, People’s Hospital, Chengdu, People’s Republic of China
Conclusion
The compound is a key intermediate for synthesizing 4(1H)-quinolone derivatives, which can be used as precursors for anti-malarial and anticancer agents.
Supporting Evidence
- The title compound is an intermediate in the synthesis of 4(1H)-quinolone-based drugs.
- These compounds can be used as precursors for anti-malarial and anticancer agents.
Takeaway
This study is about a chemical compound that can help make medicines to fight malaria and cancer.
Methodology
The compound was synthesized by refluxing a mixture of 2,2-dimethyl-1,3-dioxane-4,6-dione and methylorthoformate, followed by the addition of pyridin-2-amine.
Digital Object Identifier (DOI)
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