Combined Myocardial Stress Imaging for Detecting Heart Disease
Author Information
Author(s): Thomas Daniel, Strach Katharina, Meyer Carsten, Naehle Claas P, Schaare Sebastian, Wasmann Sven, Schild Hans H, Sommer Torsten
Primary Institution: University of Bonn
Hypothesis
Does a combined stress perfusion-tagging protocol improve the detection of coronary artery disease at 3 Tesla?
Conclusion
The combined adenosine stress perfusion-tagging protocol delivers high sensitivity and specificity for detection of significant coronary artery disease.
Supporting Evidence
- The sensitivity for detection of significant CAD by adenosine stress perfusion was 0.93.
- The specificity of adenosine stress tagging was very high at 1.0.
- The combination of both stress perfusion and stress tagging did not increase sensitivity.
- Overall accuracy for stress tagging was 0.85.
Takeaway
This study looked at a new way to check for heart disease using special imaging techniques, and it found that combining two methods works well.
Methodology
Patients underwent a combined adenosine stress perfusion and tagging protocol using a 3 Tesla MRI scanner.
Limitations
The sensitivity of adenosine stress tagging was lower compared to stress perfusion imaging.
Participant Demographics
60 patients (41 males, 19 females; 21 suspected CAD, 39 known CAD) with an average age of 54 for suspected CAD and 63 for known CAD.
Digital Object Identifier (DOI)
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