Hepatitis C Virus Infection in HIV-Infected Pregnant Women in Thailand
Author Information
Author(s): Denise J. Jamieson, Natapakwa Skunodom, Thanyanan Chaowanachan, Anuvat Roongpisuthipong, William A. Bower, Tawee Chotpitayasunondh, Wendy Bhanich Supapol, Wendi L. Kuhnert, Wimol Siriwasin, Jeffrey Wiener, Sanay Chearskul, Michelle S. McConnell, Nathan Shaffer
Primary Institution: Centers for Disease Control and Prevention
Hypothesis
What is the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among pregnant women in Thailand?
Conclusion
HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women.
Supporting Evidence
- HCV seroprevalence was 3.8% among HIV-infected pregnant women.
- Active HCV infection rate was 3.0% among HIV-infected pregnant women.
- Among HIV-uninfected pregnant women, 0.3% were HCV-infected.
- Intravenous drug use was the strongest factor associated with HCV seropositivity.
- Among 48 infants tested for HCV born to HIV/HCV coinfected women, two infants were HCV infected.
Takeaway
This study looked at pregnant women in Thailand and found that very few of them had both HIV and hepatitis C. Most of the babies born to these women were not infected with hepatitis C.
Methodology
The study tested samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies for HCV.
Limitations
The study had a small number of HIV-uninfected women and limited follow-up information for infants born to HIV-uninfected women.
Participant Demographics
The study included 1771 pregnant women, with a focus on HIV-infected and HIV-uninfected women in Bangkok, Thailand.
Statistical Information
Confidence Interval
95% CI 0.51–14.25%
Digital Object Identifier (DOI)
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