Effect of Time-Restricted Eating on Neurovascular Coupling and Metabolic Profile in Older Adults
2024

Effect of Time-Restricted Eating on Brain Blood Flow and Metabolism in Older Adults

Sample size: 6 publication Evidence: low

Author Information

Author(s): da Langley Ana Clara Costa Pinaffi, Pinto Camila Bonin, Kleszynski Keith, Tarantini Stefano, Yabluchanskiy Andriy

Primary Institution: University of Oklahoma Health Sciences

Hypothesis

Does time-restricted eating improve cerebrovascular function and metabolic profile in healthy older adults?

Conclusion

Time-restricted eating may improve brain blood flow and increase levels of important metabolites for vascular health in older adults.

Supporting Evidence

  • Time-restricted eating was associated with a significant increase in neurovascular coupling responses.
  • Participants showed increased levels of metabolites involved in vascular health after time-restricted eating.
  • The study indicates potential benefits of time-restricted eating on brain health in older adults.

Takeaway

Eating within a specific time each day might help older people have better blood flow to their brains and improve their health.

Methodology

Participants followed a 10:14 intermittent fasting regimen for 6 months, with assessments of neurovascular coupling and metabolic profile.

Potential Biases

Potential bias due to the small number of participants and lack of control group.

Limitations

The study had a small sample size and was a pilot study.

Participant Demographics

100% female, mean age: 59±5 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.3956

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