Autonomic Imbalance in Diabetes: Risks and Treatments
Author Information
Author(s): Vinik A I, Maser R E, Ziegler D
Primary Institution: Eastern Virginia Medical School, Strelitz Diabetes Research Center and Neuroendocrine Unit
Hypothesis
Is hyperglycaemia and its control the solution to the impact of autonomic imbalance on morbidity and mortality?
Conclusion
Autonomic imbalance significantly contributes to morbidity and mortality in diabetes, but restoration of balance is possible through lifestyle changes and medications.
Supporting Evidence
- Cardiac autonomic neuropathy increases morbidity and mortality in diabetes.
- Autonomic imbalance may predict the risk of sudden death.
- Therapeutic lifestyle changes can reduce the risk of autonomic dysfunction.
Takeaway
People with diabetes can have problems with their heart and nerves that make them sick. But by eating well, exercising, and taking certain medicines, they can feel better.
Methodology
The review examines various studies on autonomic dysfunction and its association with cardiovascular risk in diabetes.
Potential Biases
Potential biases in the studies reviewed may affect the conclusions drawn.
Limitations
The review is based on existing studies, which may have varying methodologies and sample sizes.
Participant Demographics
The review includes studies on individuals with Type 1 and Type 2 diabetes, as well as pre-diabetic individuals.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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