Low Prevalence of H. pylori Infection in HIV-Positive Patients
Author Information
Author(s): Fialho Andréa BC, Braga-Neto Manuel B, Guerra Eder JC, Fialho André MN, Fernandes Karine C, Sun Juliana LM, Takeda Christianne FV, Silva Cícero IS, Queiroz Dulciene MM, Braga Lucia LBC
Primary Institution: Federal University of Ceará
Hypothesis
What is the prevalence of H. pylori infection in HIV-infected patients compared to HIV-negative patients?
Conclusion
The study found that H. pylori infection was significantly lower in HIV-positive patients compared to HIV-negative ones.
Supporting Evidence
- H. pylori infection was found in 37.2% of HIV-positive patients compared to 75.2% in HIV-negative patients.
- Chronic active antral gastritis was observed in 87.6% of HIV-positive patients.
- The study was conducted in a high H. pylori prevalence area in Northeastern Brazil.
Takeaway
This study shows that fewer people with HIV have H. pylori infection compared to those without HIV, but many still have stomach problems.
Methodology
The study included 113 HIV-positive and 141 HIV-negative patients who underwent upper gastrointestinal endoscopy, with H. pylori status evaluated by urease test and histology.
Potential Biases
Potential biases may arise from the selection of participants and the reliance on self-reported data regarding symptoms and medication use.
Limitations
The study may not be generalizable to all populations due to its specific geographic focus.
Participant Demographics
The mean age of HIV-positive patients was 36 years, with 61.9% male; the control group had a mean age of 39.7 years, with 36.2% male.
Statistical Information
P-Value
p < 0.001
Statistical Significance
p < 0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website